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Bitter leaf – Medicinal Importance

Bitter Leaf, Vernonia amygdalina belongs to the plant family Compositae. In Nigeria, the Edo calls it oriwo; Hausa, chusar doki (a horse tonic food containing the leaves), fatefate/mayemaye (a food prepared from the leaves); Ibibio atidot; Igbo, onugbu; Tiv, ityuna; and Yoruba, ewuro.

Researchers say eating more of Bitter leaf soup could be the panacea for diabetes, cancer, liver damage, drug resistant microbial infections; promote safe childbirth, to mention but a few.

Indeed, a Bitter leaf-based herbal anti-diabetic medication has passed human clinical trials and received a United States Patent 6531461 for the treatment of diabetes; even as NIPRD gets set to start a multi-centre human clinical trials of a similar drug, ADI.

Also, a phytochemotherapy (treatment based on plant chemicals) for cancer made from aqueous extracts of leaves of Bitter leaf, collected in Benin City, has received a United States Patent 6849604.

Nigeria researchers have also shown that Bitter leaf protects the liver from drug induced damage. A study published in Journal of Medicinal Food suggests that Bitter leaf elicits hepatoprotectivity (offers protection against liver damage) through antioxidant (prevents cell death) activity on acetaminophen-induced hepatic damage in mice.

The roots and leaves decoction of Bitter leaf has also been shown to increase uterine contraction and motility for safer childbirth. It is traditionally used in western Uganda to treat various ailments such as treatment of painful uterus, inducing uterine contractions, management of retained placenta and post partum bleeding, malaria, induced abortion, antimicrobes (bacterial and fungal infections), infertility, colic pains and treatment of irregular and painful menstruation. 

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